Novel prognostic biomarkers in small cell lung cancer reveal mutational signatures, genomic mutations, and immune implications

Novel prognostic biomarkers in small cell lung cancer reveal mutational signatures, genomic mutations, and immune implications

Abstract Small cell lung cancer (SCLC) is a highly malignant lung cancer subtype with a dismal prognosis and limited treatment options. This study aimed to identify new prognostic molecular biomarkers for SCLC and explore their immune-related implications for treatment strategies. We analyzed 200 SC...

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Bibliographic Details
Main Authors: Yuting Li, Chen Song, Haijun Wang, Wenyu Di, Yangyang Chen, Yuanyuan Hu, Peiheng Li, Jie Chen, Yanfeng Ren, Jing Gong, Qinghua Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
SCLC
Mutational signatures
Molecular subtypes
Frequently mutated genes
Prognosticators
Immunotherapeutic potential
Online Access:https://doi.org/10.1038/s41598-025-00222-z
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https://doi.org/10.1038/s41598-025-00222-z

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