Shrimp oral immunotherapy outcomes in the phase 2 clinical trial: MOTIF

Shrimp oral immunotherapy outcomes in the phase 2 clinical trial: MOTIF

IntroductionShrimp is a common but understudied food allergen with relatively high rates of emergency department visits. Here we report the shrimp OIT outcomes in the MOTIF (NCT03504774) clinical trial and discuss some of the challenges with performing this study.MethodsIn this phase 2 clinical tria...

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Main Authors: Shirley Y. Jiang, Shu Cao, Kristine Martinez, Reyna Sharma, Olivia Raeber, Andrea Fernandes, Dinara Bogetic, Abhinav Kaushik, Sheena Gupta, Monali Manohar, Holden T. Maeker, Andrew R. Chin, Andrew J. Long, Catherine Feight, Margaret Woch, Kari C. Nadeau, R. Sharon Chinthrajah, Sayantani B. Sindher
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Allergy
Subjects:
shrimp
allergy
oral immunotherapy
clinical trial
double-blind placebo-controlled food challenge
Online Access:https://www.frontiersin.org/articles/10.3389/falgy.2025.1458131/full
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https://www.frontiersin.org/articles/10.3389/falgy.2025.1458131/full

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