Changes in lipid abundance are associated with disease progression and treatment response in chronic Trypanosoma cruzi infection

Changes in lipid abundance are associated with disease progression and treatment response in chronic Trypanosoma cruzi infection

Abstract Background Chagas disease, caused by the parasite Trypanosoma cruzi, is a zoonosis that affects more than seven million people. Current limitations on the diagnosis of the disease hinder the prognosis of patients and the evaluation of treatment efficacy, slowing the development of new thera...

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Main Authors: Juan Carlos Gabaldón-Figueira, Albert Ros-Lucas, Nieves Martínez-Peinado, Gavin Blackburn, Irene Losada-Galvan, Elizabeth Posada, Cristina Ballart, Elisa Escabia, Jordi Capellades, Oscar Yanes, María-Jesús Pinazo, Joaquim Gascón, Julio Alonso-Padilla
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Parasites & Vectors
Subjects:
Trypanosoma cruzi
Chagas disease
Treatment response
Metabolomics
Lipidomics
Phosphatidylethanolamine
Online Access:https://doi.org/10.1186/s13071-024-06548-3
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https://doi.org/10.1186/s13071-024-06548-3

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