CDK1-mediated phosphorylation of USP37 regulates SND1 stability and promotes oncogenesis in colorectal cancer

Colorectal cancer (CRC) poses a severe global health challenge with high incidence and mortality rates. USP37 has been identified as the bona fide deubiquitinase of SND1, playing a critical role in stabilizing SND1, thereby augmenting its oncogenic potential. The interaction between USP37 and SND1 w...

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Bibliographic Details
Main Authors: Liang Wu, Can Cheng, Ning Zhao, Liang Zhu, Heng Li, Jingwen Liu, Yang Wu, Xi Chen, Hanhui Yao, Lianxin Liu
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Acta Pharmaceutica Sinica B
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211383525000668
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