Use of a TaqMan Array Card for identification of enterotoxins and colonization factors directly from stool samples in an enterotoxigenic E. coli vaccine study

Use of a TaqMan Array Card for identification of enterotoxins and colonization factors directly from stool samples in an enterotoxigenic E. coli vaccine study

ABSTRACT Enterotoxigenic Escherichia coli (ETEC) is a leading cause of childhood and travelers’ diarrhea. The vaccine candidate ETVAX encompasses several ETEC colonization factors (CFs) with a hybrid LT (heat-labile toxin)/cholera toxin B subunit adjuvanted with a double-mutant LT. Stool samples fro...

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Main Authors: Jie Liu, T. Sakari Jokiranta, Nils Carlin, Suzanne Stroup, Jixian Zhang, Bjorn Sjostrand, Ann-Mari Svennerholm, Eric R. Houpt, Anu Kantele
Format: Article
Language:English
Published: American Society for Microbiology 2025-03-01
Series:Microbiology Spectrum
Subjects:
enterotoxigenic E. coli
ETVAX
TaqMan Array Card
Amplidiag
enterotoxin
colonization factor
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01870-24
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https://journals.asm.org/doi/10.1128/spectrum.01870-24

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