Immunotoxicity of Four Per- and Polyfluoroalkyl Substances Following 28-Day Oral Repeat Dosing in Rats Assessed by the Anti-Sheep Red Blood Cell IgM Response

Immunotoxicity of Four Per- and Polyfluoroalkyl Substances Following 28-Day Oral Repeat Dosing in Rats Assessed by the Anti-Sheep Red Blood Cell IgM Response

Some PFASs are immunotoxic in rodent models and associated with diminished vaccine response in exposed humans. This study assessed the immunotoxicity of four PFASs via the T cell-dependent IgM antibody response (TDAR) to sheep red blood cells (SRBCs) in adult male rats following 28-day oral repeat d...

Full description

Saved in:
Bibliographic Details
Main Authors: Michael F. Hughes, Michael J. DeVito, Grace Patlewicz, Russell S. Thomas, Linda D. Adams, Jeffrey L. Ambroso, Xi Yang, Bindu G. Upadhyay, Stefanie C. M. Burleson, Elaina M. Kenyon
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Toxics
Subjects:
perfluoroalkyl substance
polyfluoroalkyl substance
immunotoxicity
repeat dose
IgM
oral
Online Access:https://www.mdpi.com/2305-6304/13/6/490
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2305-6304/13/6/490

Similar Items