“Navigating growth challenges: A case study of radiation-induced growth retardation”

Growth hormone deficiency is a commonly observed pituitary hormone insufficiency in childhood cancer survivors who have undergone cranial radiation. It is the earliest and most prevalent deficiency, with an overall prevalence rate of 12.5 %. Patients who have received craniospinal radiation are at h...

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Main Authors: Ramya Selvam, Manjit Kour Mehta, Sivakumar N, Abhisek Bhattacharjee, Heena Agrawal, Shaleen Chandra
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Oral Oncology Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772906023001395
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author Ramya Selvam
Manjit Kour Mehta
Sivakumar N
Abhisek Bhattacharjee
Heena Agrawal
Shaleen Chandra
author_facet Ramya Selvam
Manjit Kour Mehta
Sivakumar N
Abhisek Bhattacharjee
Heena Agrawal
Shaleen Chandra
author_sort Ramya Selvam
collection DOAJ
description Growth hormone deficiency is a commonly observed pituitary hormone insufficiency in childhood cancer survivors who have undergone cranial radiation. It is the earliest and most prevalent deficiency, with an overall prevalence rate of 12.5 %. Patients who have received craniospinal radiation are at higher risk of experiencing short stature compared to those who have received only cranial radiation. The primary goal back then was achieving remission, and not minimizing adverse effects. However, with the current therapeutic modules, the adverse effects can be reduced significantly. Herein, we present a case of a 17-year-old who experienced growth retardation as a result of radiotherapy.
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institution Kabale University
issn 2772-9060
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publishDate 2024-03-01
publisher Elsevier
record_format Article
series Oral Oncology Reports
spelling doaj-art-b1f4dbbbc34e4c7c9459c59b485dc91a2025-01-09T06:15:08ZengElsevierOral Oncology Reports2772-90602024-03-019100149“Navigating growth challenges: A case study of radiation-induced growth retardation”Ramya Selvam0Manjit Kour Mehta1Sivakumar N2Abhisek Bhattacharjee3Heena Agrawal4Shaleen Chandra5Corresponding author. Oral and maxillofacial Pathologist and Oral Microbiologist, Dept of Dental Surgery, Lala Lajpat Rai Memorial Medical College, Meerut, 226003, India.; Oral and maxillofacial Pathologist and Oral Microbiologist, Dept of Dental Surgery, Lala Lajpat Rai Memorial Medical College, Meerut, IndiaOral and maxillofacial Pathologist and Oral Microbiologist, Dept of Dental Surgery, Lala Lajpat Rai Memorial Medical College, Meerut, IndiaDept of Oral & Maxillofacial Pathology and MicrobiologyCDER, AIIMS, New Delhi, India, Dept of Pediatric and Preventive Dentistry, Faculty of Dental Sciences, King George's Medical University, Lucknow, IndiaOral Medicine and Radiologist, Dept of Dental Surgery, Chaudhary Charan Singh University, Meerut, India; Oral Medicine and Radiologist, Dept of Dental Surgery, Lala Lajpat Rai Memorial Medical college, Meerut, 226003, India, Atal Bihari Vajpayee Medical University, Lucknow, IndiaGrowth hormone deficiency is a commonly observed pituitary hormone insufficiency in childhood cancer survivors who have undergone cranial radiation. It is the earliest and most prevalent deficiency, with an overall prevalence rate of 12.5 %. Patients who have received craniospinal radiation are at higher risk of experiencing short stature compared to those who have received only cranial radiation. The primary goal back then was achieving remission, and not minimizing adverse effects. However, with the current therapeutic modules, the adverse effects can be reduced significantly. Herein, we present a case of a 17-year-old who experienced growth retardation as a result of radiotherapy.http://www.sciencedirect.com/science/article/pii/S2772906023001395Growth hormone deficiencyRadiotherapyChemotherapyand growth hormone replacement therapy
spellingShingle Ramya Selvam
Manjit Kour Mehta
Sivakumar N
Abhisek Bhattacharjee
Heena Agrawal
Shaleen Chandra
“Navigating growth challenges: A case study of radiation-induced growth retardation”
Oral Oncology Reports
Growth hormone deficiency
Radiotherapy
Chemotherapy
and growth hormone replacement therapy
title “Navigating growth challenges: A case study of radiation-induced growth retardation”
title_full “Navigating growth challenges: A case study of radiation-induced growth retardation”
title_fullStr “Navigating growth challenges: A case study of radiation-induced growth retardation”
title_full_unstemmed “Navigating growth challenges: A case study of radiation-induced growth retardation”
title_short “Navigating growth challenges: A case study of radiation-induced growth retardation”
title_sort navigating growth challenges a case study of radiation induced growth retardation
topic Growth hormone deficiency
Radiotherapy
Chemotherapy
and growth hormone replacement therapy
url http://www.sciencedirect.com/science/article/pii/S2772906023001395
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