“Navigating growth challenges: A case study of radiation-induced growth retardation”
Growth hormone deficiency is a commonly observed pituitary hormone insufficiency in childhood cancer survivors who have undergone cranial radiation. It is the earliest and most prevalent deficiency, with an overall prevalence rate of 12.5 %. Patients who have received craniospinal radiation are at h...
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Elsevier
2024-03-01
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Series: | Oral Oncology Reports |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2772906023001395 |
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author | Ramya Selvam Manjit Kour Mehta Sivakumar N Abhisek Bhattacharjee Heena Agrawal Shaleen Chandra |
author_facet | Ramya Selvam Manjit Kour Mehta Sivakumar N Abhisek Bhattacharjee Heena Agrawal Shaleen Chandra |
author_sort | Ramya Selvam |
collection | DOAJ |
description | Growth hormone deficiency is a commonly observed pituitary hormone insufficiency in childhood cancer survivors who have undergone cranial radiation. It is the earliest and most prevalent deficiency, with an overall prevalence rate of 12.5 %. Patients who have received craniospinal radiation are at higher risk of experiencing short stature compared to those who have received only cranial radiation. The primary goal back then was achieving remission, and not minimizing adverse effects. However, with the current therapeutic modules, the adverse effects can be reduced significantly. Herein, we present a case of a 17-year-old who experienced growth retardation as a result of radiotherapy. |
format | Article |
id | doaj-art-b1f4dbbbc34e4c7c9459c59b485dc91a |
institution | Kabale University |
issn | 2772-9060 |
language | English |
publishDate | 2024-03-01 |
publisher | Elsevier |
record_format | Article |
series | Oral Oncology Reports |
spelling | doaj-art-b1f4dbbbc34e4c7c9459c59b485dc91a2025-01-09T06:15:08ZengElsevierOral Oncology Reports2772-90602024-03-019100149“Navigating growth challenges: A case study of radiation-induced growth retardation”Ramya Selvam0Manjit Kour Mehta1Sivakumar N2Abhisek Bhattacharjee3Heena Agrawal4Shaleen Chandra5Corresponding author. Oral and maxillofacial Pathologist and Oral Microbiologist, Dept of Dental Surgery, Lala Lajpat Rai Memorial Medical College, Meerut, 226003, India.; Oral and maxillofacial Pathologist and Oral Microbiologist, Dept of Dental Surgery, Lala Lajpat Rai Memorial Medical College, Meerut, IndiaOral and maxillofacial Pathologist and Oral Microbiologist, Dept of Dental Surgery, Lala Lajpat Rai Memorial Medical College, Meerut, IndiaDept of Oral & Maxillofacial Pathology and MicrobiologyCDER, AIIMS, New Delhi, India, Dept of Pediatric and Preventive Dentistry, Faculty of Dental Sciences, King George's Medical University, Lucknow, IndiaOral Medicine and Radiologist, Dept of Dental Surgery, Chaudhary Charan Singh University, Meerut, India; Oral Medicine and Radiologist, Dept of Dental Surgery, Lala Lajpat Rai Memorial Medical college, Meerut, 226003, India, Atal Bihari Vajpayee Medical University, Lucknow, IndiaGrowth hormone deficiency is a commonly observed pituitary hormone insufficiency in childhood cancer survivors who have undergone cranial radiation. It is the earliest and most prevalent deficiency, with an overall prevalence rate of 12.5 %. Patients who have received craniospinal radiation are at higher risk of experiencing short stature compared to those who have received only cranial radiation. The primary goal back then was achieving remission, and not minimizing adverse effects. However, with the current therapeutic modules, the adverse effects can be reduced significantly. Herein, we present a case of a 17-year-old who experienced growth retardation as a result of radiotherapy.http://www.sciencedirect.com/science/article/pii/S2772906023001395Growth hormone deficiencyRadiotherapyChemotherapyand growth hormone replacement therapy |
spellingShingle | Ramya Selvam Manjit Kour Mehta Sivakumar N Abhisek Bhattacharjee Heena Agrawal Shaleen Chandra “Navigating growth challenges: A case study of radiation-induced growth retardation” Oral Oncology Reports Growth hormone deficiency Radiotherapy Chemotherapy and growth hormone replacement therapy |
title | “Navigating growth challenges: A case study of radiation-induced growth retardation” |
title_full | “Navigating growth challenges: A case study of radiation-induced growth retardation” |
title_fullStr | “Navigating growth challenges: A case study of radiation-induced growth retardation” |
title_full_unstemmed | “Navigating growth challenges: A case study of radiation-induced growth retardation” |
title_short | “Navigating growth challenges: A case study of radiation-induced growth retardation” |
title_sort | navigating growth challenges a case study of radiation induced growth retardation |
topic | Growth hormone deficiency Radiotherapy Chemotherapy and growth hormone replacement therapy |
url | http://www.sciencedirect.com/science/article/pii/S2772906023001395 |
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