Structural mapping of polyclonal IgG responses to HA after influenza virus vaccination or infection

Structural mapping of polyclonal IgG responses to HA after influenza virus vaccination or infection

ABSTRACT Cellular and molecular characterization of immune responses elicited by influenza virus infection and seasonal vaccination have informed efforts to improve vaccine efficacy, breadth, and longevity. Here, we use negative stain electron microscopy polyclonal epitope mapping (nsEMPEM) to struc...

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Main Authors: André Nicolás León, Alesandra J. Rodriguez, Sara T. Richey, Alba Torrents de la Pena, Rachael M. Wolters, Abigail M. Jackson, Katherine Webb, C. Buddy Creech, Sandra Yoder, Philip A. Mudd, James E. Crowe, Julianna Han, Andrew B. Ward
Format: Article
Language:English
Published: American Society for Microbiology 2025-03-01
Series:mBio
Subjects:
influenza
electron microscopy
polyclonal antibodies
vaccines
adaptive immunity
Online Access:https://journals.asm.org/doi/10.1128/mbio.02030-24
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https://journals.asm.org/doi/10.1128/mbio.02030-24

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