m5C-modified circRREB1 promotes lung cancer progression by inducing mitophagy

m5C-modified circRREB1 promotes lung cancer progression by inducing mitophagy

Abstract Background Lung cancer is the most common malignant tumour and the leading cause of cancer-related death. circular RNAs (circRNAs) have important biological functions and are closely related to tumour development. The 5-methylcytosine (m5C) modification can regulate the molecular fate of RN...

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Main Authors: Dunyu Cai, Xingcai Chen, Haotian Xu, Qingyun Zhao, Xiaodong Zhou, Jiaxi Wu, Shengyi Yuan, Yihong Gao, Deqing Li, Ruirui Zhang, Wenyi Peng, Gang Li, Aruo Nan
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Lung cancer
circRREB1
m5C modification
Mitophagy
Online Access:https://doi.org/10.1186/s13046-025-03460-1
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https://doi.org/10.1186/s13046-025-03460-1

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