Differential patterns of cross-protection against antigenically distinct variants in small animal models of SARS-CoV-2 infection
Abstract Continuous evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) will likely necessitate periodic updates of vaccine composition. Based on a series of studies carried out in human ACE2 transgenic mice (K18-hACE2) and Syrian hamsters, we show that immunity at the respirat...
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| Main Authors: | Prabhuanand Selvaraj, Charles B. Stauft, Shufeng Liu, Kotou Sangare, Tony T. Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-06-01
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| Series: | npj Viruses |
| Online Access: | https://doi.org/10.1038/s44298-025-00125-w |
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