Combating Metallo-β-Lactamase-Producing <i>Pseudomonas aeruginosa</i>: The Fractional Inhibitory Concentration Index as a Tool to Evaluate Antibiotic Synergy

Combating Metallo-β-Lactamase-Producing <i>Pseudomonas aeruginosa</i>: The Fractional Inhibitory Concentration Index as a Tool to Evaluate Antibiotic Synergy

<b>Background</b>: Multi-drug-resistant Gram-negative bacteria producing metallo-β-lactamase are an increasing concern. Here, we described three cases of infection due to difficult-to-treat and drug-resistant <i>P. aeruginosa</i> producing metallo-β-lactamases, which were suc...

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Bibliographic Details
Main Authors: Guido Granata, Carolina Venditti, Claudia Rotondo, Valentina Dimartino, Silvia D’Arezzo, Assunta Gallo, Gabriella Parisi, Alessandro Capone, Carla Fontana, Stefania Cicalini
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Antibiotics
Subjects:
carbapenem-resistant <i>Pseudomonas aeruginosa</i>
metallo-β-Lactamase
IMP-13 carbapenemases
antimicrobial synergy
cefiderocol
imipenem–relebactam
Online Access:https://www.mdpi.com/2079-6382/14/2/210
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