The Role of Autophagy in Copper-Induced Apoptosis and Developmental Neurotoxicity in SH-SY5Y Cells

The Role of Autophagy in Copper-Induced Apoptosis and Developmental Neurotoxicity in SH-SY5Y Cells

Copper (Cu) is a global environmental pollutant that poses a serious threat to humans and ecosystems. Copper induces developmental neurotoxicity, but the underlying molecular mechanisms are unknown. Neurons are nonrenewable, and they are unable to mitigate the excessive accumulation of pathological...

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Bibliographic Details
Main Authors: Lu Lu, Ying Zhang, Wei Shi, Qian Zhou, Zhuoqi Lai, Yuepu Pu, Lihong Yin
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Toxics
Subjects:
copper
developmental neurotoxicity
autophagy
Wnt signaling pathway
Online Access:https://www.mdpi.com/2305-6304/13/1/63
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