Self-assembled injectable Icariin@ Ti3C2Tx/doxorubicin hydrogel preserving osteogenesis while synergizing photodynamic and chemodynamic therapy for osteosarcoma

Abstract Local therapy involving injectable hydrogel systems loaded with doxorubicin (DOX) has garnered significant attention in the realm of osteosarcoma (OS) research. Nevertheless, it has been noted that the local delivery of high-dose DOX exerts a pronounced inhibitory impact on osteogenesis, wh...

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Bibliographic Details
Main Authors: Jiahao Fu, Hao Chen, Yiqiao Zhao, Hongzhong Xi, Yixuan Huang, Chenglin Liu, Yaokun Wu, Wei Song, Xin Liu, Bin Du, Guangquan Sun
Format: Article
Language:English
Published: Springer 2025-03-01
Series:Journal of Materials Science: Materials in Medicine
Online Access:https://doi.org/10.1007/s10856-025-06874-7
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