FGF21 is a novel biomarker to predict fragility fractures in patients with type 2 diabetes mellitus

FGF21 is a novel biomarker to predict fragility fractures in patients with type 2 diabetes mellitus

Abstract Fibroblast growth factor 21 (FGF21) levels are elevated with type 2 diabetes mellitus (T2D). This study aimed to elucidate whether FGF21 is a predictor for fragility fractures and to construct a predictive model using FGF21 as a risk factor to predict fractures in T2D. This prospective coho...

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Main Authors: Mattabhorn Phimphilai, Arintaya Phrommintikul, Wanwarang Wongcharoen, Natavuth Hengjeerajarus, Krittadhee Karndumri, Nipon Chattipakorn, Siriporn C. Chattipakorn
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Biomarkers
Fibroblast growth factor 21
Fractures
Predictive model
Type 2 diabetes mellitus
Online Access:https://doi.org/10.1038/s41598-025-15104-7
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https://doi.org/10.1038/s41598-025-15104-7

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