IgSF11–RAP1 signaling promotes cell migration and invasion of cutaneous melanoma

IgSF11–RAP1 signaling promotes cell migration and invasion of cutaneous melanoma

Abstract Background Aberrant cell adhesion signaling is known to either accelerate or inhibit cancer progression, but the underlying molecular basis has yet to be established. The immunoglobulin superfamily 11 (IgSF11) functions as a cell adhesion protein and is overexpressed in several types of can...

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Bibliographic Details
Main Authors: Yasuyuki Kobayashi, Kotaro Sugimoto, Minaka Ishibashi, Makoto Kobayashi, Shohei Igari, Shigeki Kitamura, Toshiyuki Yamamoto, Yuko Hashimoto, Hideki Chiba
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cell Communication and Signaling
Subjects:
IgSF11
BT-IgSF
Junctional adhesion molecule
Tight junction
Cell adhesion signal
Malignant melanoma
Online Access:https://doi.org/10.1186/s12964-025-02245-5
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https://doi.org/10.1186/s12964-025-02245-5

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