Protein kinase B inhibitors enhance the sensitivity of translocated promoter region–fibroblast growth factor receptor 1 cells to fibroblast growth factor receptor 1 inhibitor-induced apoptosis

Objective Fibroblast growth factor receptor 1 (FGFR1) inhibitors are considered effective for treating 8p11 myeloproliferative syndrome. However, targeting FGFR1 alone may be inadequate for patients with translocated promoter region (TPR)–FGFR1 rearrangement. Methods In this study, we established TP...

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Bibliographic Details
Main Authors: Mengyao Lv, Wenbing Shangguan, Qian Zhao, Yan Li, Quan Zhao, Feng Li
Format: Article
Language:English
Published: SAGE Publishing 2025-08-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605251362968
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