Carbapenem-resistant Klebsiella pneumoniae infections in Chinese children: in vitro activities of ceftazidime-avibactam and aztreonam-avibactam against carbapenemase-producing strains in a two-center study

Carbapenem-resistant Klebsiella pneumoniae infections in Chinese children: in vitro activities of ceftazidime-avibactam and aztreonam-avibactam against carbapenemase-producing strains in a two-center study

ObjectiveThis study assessed epidemiology characteristics, carbapenem-resistance genes, and drug resistance to ceftazidime-avibactam (CZA) and aztreonam-avibactam (AZA) in children with carbapenem-resistant Klebsiella Pneumoniae (CRKP) infections.MethodsA total of 363 non-repetitive CRKP strains wer...

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Bibliographic Details
Main Authors: Xia Ran, Xue Chen, Cai Wang, Haiping Wang, Wei Xie, Chunmei Jing
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
carbapenem-resistant Klebsiella pneumoniae
ceftazidime-avibactam
aztreonam-avibactam
KPC-2
NDM-1 and NDM-5
epidemiology characteristics
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1545999/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1545999/full

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