Aβ25-35-based recombinant gene vaccine effectively improves cognitive dysfunction in Alzheimer′s disease mouse models
Objective To investigate the therapeutic effects of a newly constructed Aβ25-35-based recombinant gene vaccine for Alzheimer′s disease (AD). Methods The pcDNA-Aβ25-35-GRP94 recombinant gene vaccine was constructed using Aβ25-35 as the epitope and pcDNA3.1 plasmid as the vector. Early APP/PS1 double-...
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| Main Author: | |
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| Format: | Article |
| Language: | zho |
| Published: |
Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2025-07-01
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| Series: | Jichu yixue yu linchuang |
| Subjects: | |
| Online Access: | https://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2025-45-7-897.pdf |
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