Effect of mitochondrial oxidative stress on lead-exposed inflammatory activation of microglia

Effect of mitochondrial oxidative stress on lead-exposed inflammatory activation of microglia

Objective To investigate the role and mechanism of mitochondrial oxidative stress in lead (Pb)-induced microglial inflammation. Methods BV2 microglia cells were divided into 4 groups and treated with 0 μmol/L (control group), 1 μmol/L, 5 μmol/L and 10 μmol/L lead acetate, respectively. The mRNA expr...

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Bibliographic Details
Main Authors: ZHOU Qin, LI Lifan, HUANG Dingbang, CHEN Kaiju, ZHANG Xiaoshun, CHEN Lixuan, LI Hecheng, MENG Xiaojing
Format: Article
Language:zho
Published: Editorial Office of Journal of Guangxi Medical University 2024-07-01
Series:Guangxi Yike Daxue xuebao
Subjects:
pb
microglia
mitochondrial oxidative stress
inflammatory reaction
nlrp3 inflammasome
Online Access:https://journal.gxmu.edu.cn/article/doi/10.16190/j.cnki.45-1211/r.2024.07.001
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https://journal.gxmu.edu.cn/article/doi/10.16190/j.cnki.45-1211/r.2024.07.001

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