Validation and optimization of classification criteria for childhood-onset systemic lupus erythematosus in a multi-center Chinese cohort

Validation and optimization of classification criteria for childhood-onset systemic lupus erythematosus in a multi-center Chinese cohort

ObjectiveThis study evaluated the diagnostic accuracy of the 2012 SLICC and 2019 EULAR/ACR criteria in Chinese cSLE patients and aimed to develop an optimized classification schema based on the 2019 EULAR/ACR criteria, specifically tailored for cSLE.MethodsData from cSLE and control cases were extra...

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Main Authors: Yudi Zhang, Tian Shen, Sihao Gao, Junxia Yan, Jingcheng Shi, Xuemei Tang, Mo Wang, Jun Yang, Haiguo Yu, Huawei Mao, Lanjun Shuai, Yongzhen Li, Yan Cao, Xiaoyan Li, Ying Wang, Qian Liu, Hongmei Song, Xiaochuan Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
childhood-onset systemic lupus erythematosus
classification criteria
SLICC-2012
EULAR/ACR-2019
criteria validation
criteria optimization
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1611349/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1611349/full

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