A validated and standardized pseudotyped microneutralization assay as a safe and powerful tool to measure LASSA virus neutralising antibodies for vaccine development and comparison [version 2; peer review: 2 approved]

A validated and standardized pseudotyped microneutralization assay as a safe and powerful tool to measure LASSA virus neutralising antibodies for vaccine development and comparison [version 2; peer review: 2 approved]

Background Over the past few decades, World Health Organization (WHO) has made massive efforts to promote the development of a vaccine against Lassa virus (LASV), one of the top ten priority pathogens for research and development under the WHO R&D Blueprint for Emerging Infections. To date, seve...

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Main Authors: Alessandro Manenti, Emanuele Montomoli, Francesca Dapporto, Maria Altamura, Nigel Temperton, Pietro Piu, Claudia Semplici, Eleonora Molesti, Vittoria Forconi, Roberta Antonelli
Format: Article
Language:English
Published: F1000 Research Ltd 2024-10-01
Series:F1000Research
Subjects:
Lassa virus (LASV)
International Standard and Reference Panel for Anti-Lassa Fever
neutralisation assay
international guidelines
eng
Online Access:https://f1000research.com/articles/13-534/v2
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