Investigation of the pharmacological activity of the tetrapeptide HAEЕ, zinc, and human serum albumin in a transgenic mouse model with tau protein overexpression (P301S)

Investigation of the pharmacological activity of the tetrapeptide HAEЕ, zinc, and human serum albumin in a transgenic mouse model with tau protein overexpression (P301S)

Introduction: Neurodegenerative diseases affecting neurons represent a wide spectrum of pathological conditions. To slow the accumulation of pathological tau protein, therapeutic interventions such as a pharmaceutical composition consisting of the tetrapeptide HAEЕ, zinc, and albumin may be employed...

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Main Authors: Veronika S. Shmigerova, Yulia V. Stepenko, Alexandra A. Kurbatova, Nikita S. Zhunusov, Nikita S. Lyapkalov, Maria S. Sviridova, Tatyana V. Avtina, Arkadiy V. Nesterov, Alexander A. Popov, Natalia I. Nesterova, Mariia Iu. Goltsova, Tatiana G. Pokrovskaya
Format: Article
Language:English
Published: Belgorod National Research University 2025-03-01
Series:Research Results in Pharmacology
Subjects:
tauopathy
tau protein
behavioral activity
transgenic mice
haee-zn-hsa complex pharmaceutical composition
Online Access:https://rrpharmacology.ru/index.php/journal/article/view/493
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