DNA Replication and Polymer Chain Duplication Reshape the Genome in Space and Time

In eukaryotes, DNA replication constitutes a complex process whereby multiple origins are stochastically fired, and from which the replication machinery proceeds along chromosomes to achieve the faithful synthesis of two identical copies of the genome during the S phase of the cell cycle. Experiment...

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Bibliographic Details
Main Authors: Dario D’Asaro, Maxime M. C. Tortora, Cédric Vaillant, Jean-Michel Arbona, Daniel Jost
Format: Article
Language:English
Published: American Physical Society 2024-10-01
Series:Physical Review X
Online Access:http://doi.org/10.1103/PhysRevX.14.041020
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