Patient-specific gene co-expression networks reveal novel subtypes and predictive biomarkers in lung adenocarcinoma
Abstract Lung adenocarcinoma (LUAD) is a highly heterogenous and aggressive form of non-small cell lung cancer (NSCLC). The use of genome-wide gene co-expression networks (GCNs) has been paramount to describe changes in the transcriptional regulatory programs found between diseased and healthy state...
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| Main Authors: | Patricio López-Sánchez, Federico Ávila-Moreno, Enrique Hernández-Lemus, Marieke L. Kuijjer, Jesús Espinal-Enríquez |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
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| Series: | npj Systems Biology and Applications |
| Online Access: | https://doi.org/10.1038/s41540-025-00522-0 |
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