Patient-specific gene co-expression networks reveal novel subtypes and predictive biomarkers in lung adenocarcinoma

Abstract Lung adenocarcinoma (LUAD) is a highly heterogenous and aggressive form of non-small cell lung cancer (NSCLC). The use of genome-wide gene co-expression networks (GCNs) has been paramount to describe changes in the transcriptional regulatory programs found between diseased and healthy state...

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Bibliographic Details
Main Authors: Patricio López-Sánchez, Federico Ávila-Moreno, Enrique Hernández-Lemus, Marieke L. Kuijjer, Jesús Espinal-Enríquez
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-025-00522-0
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