Mitigation of sepsis-induced liver injury by Clemastine via modulating GSDMD/NLRP-3/Caspase-1/NF-κB signalling pathways
Abstract Aims Nearly 48 million people have sepsis every year, and 11 million lose their lives as a direct consequence of the disease. In addition, sepsis is still the fifth leading death cause globally. The objective of this research was to find out whether pretreatment with Clemastine (CLM) would...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
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| Series: | European Journal of Medical Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40001-025-02982-w |
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