Discrete and conserved inflammatory signatures drive thrombosis in different organs after Salmonella infection

Abstract Inflammation-induced thrombosis is a common consequence of bacterial infections, such as those caused by Salmonella Typhimurium (STm). The presentation of multi-organ thrombosis post-infection that develops and resolves with organ-specific kinetics raises significant challenges for its ther...

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Main Authors: Marisol Perez-Toledo, Nonantzin Beristain-Covarrubias, Jamie Pillaye, Ruby R. Persaud, Edith Marcial-Juarez, Sian E. Jossi, Jessica R. Hitchcock, Areej Alshayea, William M. Channell, Niek T. J. Wiersma, Rachel E. Lamerton, Dean P. Kavanagh, Agostina Carestia, William G. Horsnell, Ian R. Henderson, Nigel Mackman, Andrew R. Clark, Craig N. Jenne, Julie Rayes, Steve P. Watson, Adam F. Cunningham
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57466-6
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