Effect of high glucose on the gene expression profiling in cardiac fibroblasts from rats at different ages

Effect of high glucose on the gene expression profiling in cardiac fibroblasts from rats at different ages

Background Cardiac fibroblasts (CFs) play a vital role in the physiological and pathological processes of the heart. Previous studies have demonstrated that high glucose stimulation induces the transformation of CFs into myofibroblasts, contributing to cardiac fibrogenesis. However, in vivo experime...

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Bibliographic Details
Main Authors: Quqian Mo, Angyu Zhan, Ruining Bai, Shaoling Lin, Jiaojiao Feng, Tongjun Li, Zijian Lao, Xiao Yang, Keke Wang, Xianglu Rong, Lexun Wang
Format: Article
Language:English
Published: PeerJ Inc. 2025-03-01
Series:PeerJ
Subjects:
Cardiac fibroblast
High glucose
Cardiac fibrosis
Gene expression profiling
RNA-seq
Online Access:https://peerj.com/articles/19040.pdf
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