High CTLA-4 gene expression is an independent good prognosis factor in breast cancer patients, especially in the HER2-enriched subtype

High CTLA-4 gene expression is an independent good prognosis factor in breast cancer patients, especially in the HER2-enriched subtype

Abstract Background Breast cancer (BC) is the most common cancer in women and the leading cause of cancer-related death worldwide. This heterogeneous disease has been historically considered a non-immunogenic type of cancer. However, recent advances in immunotherapy have increased the interest in kn...

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Main Authors: Yoel G. Montoyo-Pujol, José J. Ponce, Silvia Delgado-García, Tina A. Martín, Hortensia Ballester, Elena Castellón-Molla, Angela Ramos-Montoya, Inmaculada Lozano-Cubo, J. Miguel Sempere-Ortells, Gloria Peiró
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Cancer Cell International
Subjects:
Breast carcinoma
Immune checkpoints
mRNA expression
CTLA-4
HER2-enriched
Online Access:https://doi.org/10.1186/s12935-024-03554-4
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https://doi.org/10.1186/s12935-024-03554-4

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