Optimized Production of High-Titer Recombinant Adeno-Associated Virus in Roller Bottles

Adeno-associated viral (AAV) vectors are used for in vivo gene transfer in a number of preclinical models of genetic diseases (including large-animal models) and are currently being tested in clinical trials for treatment of hemophilia B and cystic fibrosis. Protocols for production of AAV vectors i...

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Bibliographic Details
Main Authors: Y.-L. Liu, K. Wagner, N. Robinson, D. Sabatino, P. Margaritis, W. Xiao, R.W. Herzog
Format: Article
Language:English
Published: Taylor & Francis Group 2003-01-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/03341dd07
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