Quantitative Detection of Low-Copy-Number mRNAs Differing at Single Nucleotide Positions

Accurate analysis of mRNA expression levels of SNPs, highly homologous genes, and splicing variants requires techniques capable of quantifying low-copy-number mRNAs differing at single nucleotide positions. We have used an RT-PCR-based technique based on co-amplification of closely related target mR...

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Bibliographic Details
Main Authors: J. Stenman, S. Lintula, O. Rissanen, P. Finne, J. Hedström, A. Palotie, A. Orpana
Format: Article
Language:English
Published: Taylor & Francis Group 2003-01-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/03341dd05
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