O-GlcNAcylation on serine 40 of histone H2A promotes proliferation and invasion in triple-negative breast cancer

Abstract Triple-negative breast cancer (TNBC) is characterized by resistance to conventional treatment and a poor prognosis. The O-linked β-N-acetylglucosamine (O-GlcNAc) modification of proteins has been reported to affect cancer progression. However, the key O-GlcNAc proteins involved in TNBC phen...

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Bibliographic Details
Main Authors: Yoko Uno, Koji Hayakawa
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-95394-z
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