Fabrication and evaluation of solidified nanoemulsion designs for systemic delivery of atorvastatin through the lung

Abstract To improve the solubility of atorvastatin and overcome the stability issues of liquid nanoemulsion, the current study aimed to synthesize solidified SNEDDS particles with aerodynamic diameter of ≤ 3 μm. The simple and chitosan-decorated liquid SNEDDS were dried by spray drying method and ev...

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Bibliographic Details
Main Authors: Muhammad Danish Saeed, Kifayat Ullah Shah, Asif Nawaz, Faiqa Falak Naz, Amira Metouekel, Gamal A. Shazly, Musaab Dauelbait
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-05646-1
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