Protective effects of sumatriptan against optic nerve injury in rats via modulation of kynurenine pathway, oxidative stress and apoptosis

Protective effects of sumatriptan against optic nerve injury in rats via modulation of kynurenine pathway, oxidative stress and apoptosis

Introduction: Traumatic optic neuropathy (TON) is an acute visual dysfunction subsequent to head and neck trauma. Despite immense efforts, there is no effective treatment to minimize the damage caused by TON. Due to its anti-inflammatory and neuroprotective properties, we aimed to measure the effect...

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Main Authors: Moein Ala, Razieh Mohammad Jafari, Leila Aghajanpour, Mehdi Sanatkar, Masoud Aghsaei Fard, Sepideh Goudarzi, Amir Shadboorestan, Ahmad Reza Dehpour
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2024-08-01
Series:BioImpacts
Subjects:
sumatriptan
traumatic optic neuropathy
kynurenine
retina
rgc
ido1
Online Access:https://bi.tbzmed.ac.ir/PDF/bi-15-30409.pdf
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https://bi.tbzmed.ac.ir/PDF/bi-15-30409.pdf

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