NOX2/NLRP3-Inflammasome-Dependent Microglia Activation Promotes As(III)-Induced Learning and Memory Impairments in Developmental Rats

NOX2/NLRP3-Inflammasome-Dependent Microglia Activation Promotes As(III)-Induced Learning and Memory Impairments in Developmental Rats

Inorganic arsenic [As(III) and As(V)] is a pervasive environmental contaminant in groundwater systems, early-life exposure to which is associated with an impaired cognitive ability and an increased risk of neurobehavioral disorders. Although the effect of As(III) on the neurons is well studied, the...

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Bibliographic Details
Main Authors: Linlin Zhang, Yuyao Xiao, Dan Wang, Xuerong Han, Ruoqi Zhou, Huiying Zhang, Kexin Zhu, Junyao Wu, Xiance Sun, Shuangyue Li
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Toxics
Subjects:
inorganic arsenic
microglia
NLRP3 inflammasome
NOX2
learning and memory
Online Access:https://www.mdpi.com/2305-6304/13/7/538
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