The SWELL1 Channel Promotes Ischemic Brain Damage by Mediating Neuronal Swelling and Glutamate Toxicity
Abstract Cytotoxic neuronal swelling and glutamate excitotoxicity are two hallmarks of ischemic stroke. However, the underlying molecular mechanisms are not well understood. Here, it is reported that SWELL1, the essential subunit of the volume‐regulated anion channel (VRAC), plays a dual role in isc...
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| Main Authors: | Jianan Chen, Junhua Yang, Jiachen Chu, Kevin Hong Chen, Jesse Alt, Rana Rais, Zhaozhu Qiu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-09-01
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| Series: | Advanced Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/advs.202401085 |
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