Involvement of ionomic metabolism of both the cerebrospinal fluid and the spinal cord in the analgesic efficacy of matrine in rats

Involvement of ionomic metabolism of both the cerebrospinal fluid and the spinal cord in the analgesic efficacy of matrine in rats

Context Matrine has antinociceptive properties, and spinal cord ionomic changes are involved in bone cancer pain.Objective To investigate the relationship between ionomic metabolism in cerebrospinal fluid (CSF) and spinal cord and matrine’s analgesic efficacy.Materials and methods The antinociceptiv...

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Main Authors: Jin-Lu Huang, Chen-Yue Tang, Yao Fu, Li-Li Wan, Jie Li, Xi-Peng Sun, Jia-Lu Hu, Yue-Yi Zhang, Li-Ying Qu, Miao-Jia Fu, Yuan-Yuan Zhang, Le Ma, Cheng Guo, Jiu-Geng Chen
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Pharmaceutical Biology
Subjects:
Matrine
inflammatory pain
ionomic metabolism
cerebrospinal fluid
spinal cord
Online Access:https://www.tandfonline.com/doi/10.1080/13880209.2025.2492872
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https://www.tandfonline.com/doi/10.1080/13880209.2025.2492872

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