A naphthalimide derivative exerts potent antiplatelet and antithrombotic activities without a bleeding tendency

A naphthalimide derivative exerts potent antiplatelet and antithrombotic activities without a bleeding tendency

BackgroundBleeding is the inherent adverse effect of antiplatelet drugs that has limited their use in the prevention of secondary heart attack and stroke. Thus, finding a novel antiplatelet drug with antithrombotic activities while preserving hemostatic function remains a crucial issue. Here, we scr...

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Bibliographic Details
Main Authors: Wan-Jung Lu, Jiun-Yi Li, Tzenge-Lien Shih, Ray-Jade Chen, Ting-Yu Chen, Wei-Ting Kao, Jen-Wei Liu, Hsueh-Hsiao Wang, Hsien-Yu Peng, Kuan-Hung Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
Subjects:
GPVI
naphthalimide derivative
platelet activation
thrombus formation
antiplatelet agent
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1541255/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1541255/full

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