A Network Pharmacology Study and Experimental Validation to Identify the Potential Mechanism of Heparan Sulfate on Alzheimer’s Disease-Related Neuroinflammation

A Network Pharmacology Study and Experimental Validation to Identify the Potential Mechanism of Heparan Sulfate on Alzheimer’s Disease-Related Neuroinflammation

Background/Objectives: Heparan sulfate (HS) is a polysaccharide that is found on the surface of cells and has various biological functions in the body. Methods: The purpose of this study was to predict the pharmacological effects and molecular mechanisms of HS on Alzheimer’s disease (AD) and neuroin...

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Bibliographic Details
Main Authors: Dong-Uk Kim, Bitna Kweon, Jinyoung Oh, Yebin Lim, Gyeongran Noh, Jihyun Yu, Hyang-Rin Kang, Tackmin Kwon, Kwang youll Lee, Gi-Sang Bae
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Biomedicines
Subjects:
heparan sulfate
neuroinflammation
Alzheimer’s disease
network pharmacology
BV2
Online Access:https://www.mdpi.com/2227-9059/13/1/103
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