Synthesis of novel derivatives from machilin C/D as antiproliferative agents against triple negative breast cancer

Lignans are small polyphenolic compounds that play an active role in plant defense against pathogens and predators. Recently, lignan machilin D was reported to be effective as an anti-tumorigenic agent in triple negative breast cancer (TNBC) tumor-bearing mice. Previous studies have relied on plant-...

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Bibliographic Details
Main Authors: Alyson M. Ackerman, Chibuzor Olewele, Bert C. Lynn, Samuel G. Awuah
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:European Journal of Medicinal Chemistry Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772417425000287
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