Umbilical Cord Mesenchymal Stem Cells-Derived Exosomes Promote the Repair of Endometrial Injury via the miR-21-5p/PTEN/AKT Axis

Conclusion: hUCMSC-Exos ameliorated the damaged uterus, increased the number of glands and embryo implantation rates, suppressed apoptosis, and improved the cell proliferation in the mouse injured endometrium model. Exosomal miR-21-5p positively regulated the repair of endometrial injury and enhance...

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Bibliographic Details
Main Authors: Ziwei Li, Hao Ding, Liu Dong, Xiaohua Jiang, Xuan Xu, Zhen Yu, Qiong Xing, Heng Tang, Zhaolian Wei, Jianye Wang
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/sci/7674219
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