High tumor expression of CTLA4 identifies lymph node-negative basal-like breast cancer patients with excellent prognosis

High tumor expression of CTLA4 identifies lymph node-negative basal-like breast cancer patients with excellent prognosis

Abstract Background Tumor immune cell infiltration is a favorable prognostic factor in triple-negative breast cancer. Most triple-negative tumors belong to the aggressive basal-like subtype. We hypothesized that immune gene expression may identify low-risk patients for whom adjuvant chemotherapy can...

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Main Authors: Andreas Hagen Røssevold, Xavier Tekpli, Ole Christian Lingjærde, Hege G. Russnes, Johan Vallon-Christersson, Elin Borgen, Jon Lømo, Øystein Garred, Esmaeil Dorraji, Vessela N. Kristensen, Bjørn Naume, Jon Amund Kyte
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-025-00865-z
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https://doi.org/10.1038/s43856-025-00865-z

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