Naringin mitigates experimental autoimmune prostatitis by modulating oxidative stress and the NLRP3 inflammasome via the PPAR-γ/NF-κB pathway

Naringin mitigates experimental autoimmune prostatitis by modulating oxidative stress and the NLRP3 inflammasome via the PPAR-γ/NF-κB pathway

Abstract Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a debilitating condition characterized by pelvic pain and discomfort, necessitating the exploration of effective therapeutic strategies. This study aimed to elucidate the therapeutic potential of naringin (NAR) in addressing CP/C...

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Bibliographic Details
Main Authors: Wang Zhou, Xi-Ran Zhang, Xia-Chuan Qin, Yu-Chen Xie, Di Zhang, Zi-Cheng Wang, Chao-Xue Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
CP/CPPS
NLRP3 inflammasome
Naringin
PPARγ
Oxidative stress
Online Access:https://doi.org/10.1038/s41598-025-04916-2
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https://doi.org/10.1038/s41598-025-04916-2

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