Mucosal barrier injury as an independent risk factor for laboratory-confirmed bloodstream infection in patients with hematological malignancies: a real-world study

Mucosal barrier injury as an independent risk factor for laboratory-confirmed bloodstream infection in patients with hematological malignancies: a real-world study

Abstract Background Hematological malignancy (HM) patients are at high risk of bloodstream infections (BSIs) due to chemotherapy-induced mucosal barrier injury (MBI), invasive procedures, and prolonged antimicrobial exposure. While conventional nosocomial infection paradigms emphasize catheter-relat...

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Bibliographic Details
Main Authors: Mengna Liu, Xi Jiang, Yingqi Pi, Mingming Chen, Xiuqin Ren, Xinlu Dai, Yixian Wu, Yanrong Guo, Xinyi Zhang, Xiaoying Xie, Zhaofan Luo
Format: Article
Language:English
Published: BMC 2025-07-01
Series:European Journal of Medical Research
Subjects:
Hematologic malignancies
Mucosal barrier injury
Bloodstream infection
Antimicrobial resistance
Neutropenia
Online Access:https://doi.org/10.1186/s40001-025-02913-9
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https://doi.org/10.1186/s40001-025-02913-9

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