In vivo transplantation of mammalian vascular organoids onto the chick chorioallantoic membrane reveals the formation of a hierarchical vascular network

Abstract The dynamic remodeling of the nascent vascular network into a mature hierarchy is essential for embryo survival. Cell behaviors and signaling mechanisms are often investigated with animal models and perfused microchannels, giving insights into this process. To support these studies and enri...

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Bibliographic Details
Main Authors: William J. Kowalski, Shravani Vatti, Tyler Sakamoto, Wenling Li, Sarah Rose Odutola, Chengyu Liu, Guibin Chen, Manfred Boehm, Yoh-suke Mukouyama
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-91826-y
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