Association Between Genetic Variants in <i>TNF</i>, <i>IL6</i>, and <i>IL1B</i> Genes and Severity of COVID-19: A Cross-Sectional Study of Patients from Southern Brazil

Association Between Genetic Variants in <i>TNF</i>, <i>IL6</i>, and <i>IL1B</i> Genes and Severity of COVID-19: A Cross-Sectional Study of Patients from Southern Brazil

<b>Background/Objectives:</b> Genetic variants in cytokine genes such as <i>IL1B</i>, <i>IL6</i>, and <i>TNF</i> may influence inflammatory responses to SARS-CoV-2 and affect disease severity. This study investigates the role of these variants in relat...

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Main Authors: Mariléa Furtado Feira, Renan Cesar Sbruzzi, Miriãn Ferrão Maciel-Fiuza, Vitória Carolina Griebeler, Tatiana Schaffer Gregianini, Letícia Garay Martins, Nathan Araujo Cadore, Jose Artur Bogo Chies, Thayne Woycinck Kowalski, Fernanda Sales Luiz Vianna
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Diagnostics
Subjects:
SARS-CoV-2
inflammatory response
genetic polymorphisms
disease severity
Brazilian population
Online Access:https://www.mdpi.com/2075-4418/15/11/1403
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https://www.mdpi.com/2075-4418/15/11/1403

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