EXOGENOUS AND ENDOGENOUS FACTORS IN ATHEROSCLEROSIS PATHOGENESIS. RECEPTOR THEORY OF ATHEROGENESIS

The evidence on the role of Toll-like receptors (TLR) and their ligands in atherosclerosis development has been summarised. Bacterial lipopolysaccharides (LPS) could interact with TLR4 and induce macrophage transformation into foam cells, triggering atherosclerotic lesion development in the vascular...

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Bibliographic Details
Main Authors: V. G. Likhoded, V. M. Bondarenko, A. L. Gintzburg
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2010-04-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/1445
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