Neuronal PRDX-2-Mediated ROS Signaling Regulates Food Digestion via peripheral UPRmt Activation

Abstract All organisms depend on food digestion for survival, yet the brain-gut signaling mechanisms that regulate this process are not fully understood. Here, using an established C. elegans digestion model, we uncover a pathway in which neuronal ROS (free radicals) signal the intestine to suppress...

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Bibliographic Details
Main Authors: Yating Liu, Qian Li, Guojing Tian, Xinyi Zhou, Panpan Chen, Bo Chen, Zhao Shan, Bin Qi
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55013-3
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