Identification of Phytosphingosine-Based 1-<i>O</i>-Acylceramide in Human Stratum Corneum and Investigation of Its Role in Skin Barrier

Identification of Phytosphingosine-Based 1-<i>O</i>-Acylceramide in Human Stratum Corneum and Investigation of Its Role in Skin Barrier

Phytosphingosine-based 1-<i>O</i>-acylceramide (CerENP) from the human stratum corneum has not been reported on. High-resolution mass spectrometry was used to identify CerENP from skin samples. A vehicle-controlled human study was performed to investigate the physiological interaction be...

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Bibliographic Details
Main Authors: Bae-Gon Kang, Hyun Kyung Choi, Kwang-Hyeon Liu, Sung Kyu Hong, Jin Wook Kim, Eun Ok Lee, Chang Seo Park
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Cosmetics
Subjects:
1-<i>O</i>-acylceramide
CerENP
identification
skin barrier
boosting effect
Online Access:https://www.mdpi.com/2079-9284/12/2/47
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